Description

4-(Difluoromethoxy)-2-Fluorobenzoic acid is a high-value fluorinated benzoic acid derivative, serving as a critical building block in advanced organic synthesis. Its unique difluoromethoxy and fluorine substituents make it an essential intermediate for developing novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily targeted at R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate fluorinated motifs for enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: Key synthon for the research and development of new drug candidates, particularly in oncology, CNS, and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the difluoromethoxy group improves efficacy and environmental profile.
• Liquid Crystal Materials: Serves as a precursor for fluorinated liquid crystal compounds used in display technologies.
• Organic Electronic Materials: Building block for synthesizing fluorinated organic semiconductors and charge-transport materials.
• Chemical Research: Valuable reagent in academic and industrial laboratories for exploring new fluorination methodologies and structure-activity relationships.
• Custom Synthesis: Starting material for the contract manufacturing of complex, fluorinated target molecules for various industrial applications.

Basic Information

Product Name	4-(Difluoromethoxy)-2-Fluorobenzoic acid
CAS No.	1214347-60-0
Molecular Formula	C8H5F3O3
Molecular Weight	206.12 g/mol
Synonyms	2-Fluoro-4-(difluoromethoxy)benzoic Acid; Benzoic acid, 2-fluoro-4-(difluoromethoxy)-; 4-(Difluoromethoxy)-2-fluorobenzoic Acid; 2-Fluoro-4-difluoromethoxybenzoic Acid; 1214347-60-0; DFMOB Acid
EINECS	Contact for details

Quality Control

Our 4-(Difluoromethoxy)-2-Fluorobenzoic acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.