Description

Methyl 3-Chloro-4-(Trifluoromethyl)Benzoate is a high-purity, versatile benzoate ester derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its trifluoromethyl and chloro substituents, which are key functional groups for modulating the physicochemical and biological properties of target molecules. It is primarily sought after by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting new therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances bioactivity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing specialized aromatic compounds used in electronic displays and organic light-emitting diodes.
• Polymer & Resin Modifier: Employed to introduce halogenated aromatic structures into polymers, altering thermal stability, flame retardancy, and solubility properties.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions (e.g., Suzuki, Stille) and ester hydrolysis/transformation reactions to create complex molecular architectures.
• Chemical Research & Development: Essential for academic and industrial R&D labs exploring new synthetic methodologies and structure-activity relationships.

Basic Information

Product Name	Methyl 3-Chloro-4-(Trifluoromethyl)Benzoate
CAS No.	1214345-68-2
Molecular Formula	C9H6ClF3O2
Molecular Weight	238.59 g/mol
Synonyms	Methyl 3-Chloro-α,α,α-trifluoro-p-toluate; 3-Chloro-4-(trifluoromethyl)benzoic Acid Methyl Ester; Benzoic acid, 3-chloro-4-(trifluoromethyl)-, methyl ester; Methyl 3-chloro-4-trifluoromethylbenzoate; 3-Chloro-α,α,α-trifluoro-p-toluic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our production of Methyl 3-Chloro-4-(Trifluoromethyl)Benzoate adheres to stringent in-process controls and final batch analysis to ensure consistent high purity and reliability. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, identity, and impurity profiles. We support cGMP and ISO 9001 compliant manufacturing practices, and specifications can be tailored to meet specific project requirements for pharmaceutical or advanced material applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.