Description

Methyl 2-Fluoro-3-Hydroxybenzoate CAS NO 1214324-64-7 is a high-purity fluorinated aromatic ester building block of significant interest in advanced organic synthesis. This compound matters for its precise molecular architecture, featuring both a fluorine substituent and a phenolic hydroxyl group protected as a methyl ester, which enables selective derivatization. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, particularly in kinase inhibitor and anti-inflammatory research.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal Materials: Serves as a precursor for fluorinated benzoic acid derivatives used in electronic display technologies.
• Polymer Chemistry: Acts as a monomer or modifier for introducing fluorine and aromatic ester functionality into specialty polymers.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions, ester hydrolysis, and etherification to construct more complex fluorinated molecules.
• Chemical Research & Development: Employed in academic and industrial labs for method development and exploring new fluorination chemistry pathways.

Basic Information

Item	Details
Product Name	Methyl 2-Fluoro-3-Hydroxybenzoate
CAS No.	1214324-64-7
Molecular Formula	C8H7FO3
Molecular Weight	170.14 g/mol
Synonyms	2-Fluoro-3-hydroxybenzoic acid methyl ester; Methyl 2-fluoro-3-hydroxybenzoate; 3-Hydroxy-2-fluorobenzoic acid methyl ester; Benzoic acid, 2-fluoro-3-hydroxy-, methyl ester; Methyl 3-hydroxy-2-fluorobenzoate; 2-Fluoro-3-methoxycarbonylphenol; Methyl ester of 2-fluoro-3-hydroxybenzoic acid
EINECS	Contact for details

Quality Control

Our Methyl 2-Fluoro-3-Hydroxybenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with complete chromatographic data are provided for every shipment, supporting your R&D and scale-up activities with reliable and traceable material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. The container must be kept tightly closed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.