Description

3,5-Difluoro-4-(Hydroxymethyl)Benzoicacid is a high-value, multi-functional aromatic building block featuring both a carboxylic acid and a hydroxymethyl group on a difluorinated benzene ring. This unique structure makes it a critical intermediate for the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is essential for medicinal chemists and process development scientists working on novel active ingredients, where its fluorine atoms and derivatizable handles are leveraged to fine-tune potency, metabolic stability, and bioavailability.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially in oncology, CNS, and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated monomers used in electronic display technologies and organic light-emitting diodes (OLEDs).
• Polymer Modification: Incorporated as a functional monomer to create specialty polymers with enhanced chemical resistance, surface properties, or biocompatibility.
• Chemical Research & Development: A versatile building block in organic synthesis for constructing complex fluorinated aromatic compounds in academic and industrial R&D settings.
• Diagnostic Reagent Precursor: Utilized in the synthesis of fluorinated probes and tags for bioimaging and diagnostic assays.

Basic Information

Product Name	3,5-Difluoro-4-(Hydroxymethyl)Benzoicacid
CAS No.	1211596-29-0
Molecular Formula	C8H6F2O3
Molecular Weight	188.13 g/mol
Synonyms	4-(Hydroxymethyl)-3,5-difluorobenzoic Acid; 3,5-Difluoro-4-(hydroxymethyl)benzoic Acid; Benzoic acid, 3,5-difluoro-4-(hydroxymethyl)-; 1211596-29-0; 3,5-Difluoro-4-(hydroxymethyl)benzoic acid; 4-Carboxy-2,6-difluorobenzyl alcohol
EINECS	Contact for details

Quality Control

Our 3,5-Difluoro-4-(Hydroxymethyl)Benzoicacid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing all specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert gas purging to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.