Description

5-Bromo-2-Chloro-4-Fluoro-Benzoic Acid is a high-purity halogenated benzoic acid derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its precise substitution pattern, which makes it an essential intermediate for constructing complex molecules with specific electronic and steric properties. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of novel herbicides and fungicides, leveraging its halogenated structure for bioactivity.
• Ligand and Material Science: Serves as a starting material for creating specialized ligands in catalysis and for synthesizing advanced organic materials.
• Chemical Research: A versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical development projects.

Basic Information

Product Name	5-Bromo-2-Chloro-4-Fluoro-Benzoic Acid
CAS No.	1204219-98-6
Molecular Formula	C7H3BrClFO2
Molecular Weight	253.45 g/mol
Synonyms	5-Bromo-2-chloro-4-fluorobenzoic acid; 2-Chloro-5-bromo-4-fluorobenzoic acid; 4-Fluoro-5-bromo-2-chlorobenzoic acid; Benzoic acid, 5-bromo-2-chloro-4-fluoro-; 1204219-98-6; 5-Br-2-Cl-4-F-BA
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Chloro-4-Fluoro-Benzoic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment supports applications requiring high standards, including cGMP for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Purity (HPLC, Area %)	≥99.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.