Description

2,6-Difluoro-4-Methylbenzoic Acid is a high-purity fluorinated benzoic acid derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of fluorine atoms and the methyl group on the aromatic ring, which are essential for modulating the electronic properties, lipophilicity, and metabolic stability of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting kinase inhibitors, anti-inflammatory agents, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators, where the difluoro-methyl benzoate structure contributes to biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for display technologies, where its structure helps fine-tune the mesomorphic properties.
• Organic Electronic Materials: Employed in the development of novel organic semiconductors and charge-transport materials for applications in OLEDs and organic photovoltaics.
• Chemical Research & Development: A versatile reagent for Suzuki-Miyaura and other cross-coupling reactions to create complex, poly-substituted aromatic systems for various high-value applications.
• Fluorine Chemistry Studies: Used as a standard or reference compound in academic and industrial research focused on understanding the effects of fluorine substitution in aromatic systems.

Basic Information

Product Name	2,6-Difluoro-4-Methylbenzoic Acid
CAS No.	1201597-23-0
Molecular Formula	C8H6F2O2
Molecular Weight	172.13 g/mol
Synonyms	4-Methyl-2,6-difluorobenzoic Acid; 2,6-Difluoro-p-toluic Acid; Benzoic acid, 2,6-difluoro-4-methyl-; 2,6-Difluoro-4-methylbenzoic acid; 2,6-Difluoro-4-toluic acid; 4-Methyl-2,6-difluorobenzoic acid; 1201597-23-0 (CAS)
EINECS	Contact for details

Quality Control

Our 2,6-Difluoro-4-Methylbenzoic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.