Description

2-Carboxy-5-Fluorobenzeneboronic Acid Pinacol Ester is a high-value, multifunctional boronic ester derivative used as a key synthetic intermediate. Its core value lies in enabling precise Suzuki-Miyaura cross-coupling reactions, a cornerstone of modern pharmaceutical and agrochemical synthesis. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials industries who require a reliable, high-purity building block for constructing complex fluorinated aromatic structures.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs containing fluorinated benzene rings.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that leverage the fluorinated aromatic moiety.
• Material Science: Serves as a monomer or precursor in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D labs exploring new carbon-carbon bond formation methodologies.
• Fluorinated Compound Libraries: Enables the efficient construction of diverse fluorinated compound libraries for high-throughput screening in drug discovery.
• Diagnostic Reagent Precursor: Potential use in synthesizing probes and labeling agents for biochemical and diagnostic applications.

Basic Information

Product Name	2-Carboxy-5-Fluorobenzeneboronic Acid Pinacol Ester
CAS No.	1191063-57-6
Molecular Formula	C₁₃H₁₆BFO₄
Molecular Weight	266.08 g/mol
Synonyms	5-Fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic Acid; 2-Carboxy-5-fluorophenylboronic Acid Pinacol Ester; (5-Fluoro-2-carboxyphenyl)boronic Acid Pinacol Ester; 5-Fluoro-2-(pinacolatoboryl)benzoic Acid; 2-Borono-5-fluorobenzoic Acid Pinacol Ester; 5-Fluoro-2-((4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl))benzoic Acid; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-5-fluorobenzoic Acid
EINECS	Contact for details

Quality Control

Our 2-Carboxy-5-Fluorobenzeneboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.