Description

2,4,5-Trifluoro-n-Methoxy-n-Methylbenzamide is a high-purity fluorinated aromatic amide building block of significant interest in advanced organic synthesis. Its value lies in its unique trifluoromethyl and methoxy substitution pattern, which is strategically leveraged to modulate the physicochemical properties of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients, where its fluorine atoms can enhance metabolic stability, bioavailability, and binding affinity.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in oncology, CNS, and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the design and production of advanced herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science Research: Serves as a precursor for developing specialty polymers, liquid crystals, and organic electronic materials due to its fluorine content.
• Chemical Biology & Proteomics: Employed as a building block for synthesizing molecular probes and activity-based protein profiling (ABPP) reagents.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for client-specific projects requiring complex fluorinated aromatic structures.
• Academic Research: Utilized in university and institutional labs for methodological studies in fluorination chemistry and heterocycle formation.

Basic Information

Product Name	2,4,5-Trifluoro-n-Methoxy-n-Methylbenzamide
CAS No.	1189175-49-2
Molecular Formula	C9H7F3NO2
Molecular Weight	218.15 g/mol
Synonyms	2,4,5-Trifluoro-N-methoxy-N-methylbenzamide; N-Methoxy-N-methyl-2,4,5-trifluorobenzamide; 2,4,5-Trifluorobenzoic Acid N-Methoxy-N-methylamide; 2,4,5-Trifluoro-N-methoxy-N-methyl-benzamide; 1189175-49-2; Benzamide, 2,4,5-trifluoro-N-methoxy-N-methyl-; N-Methoxy-N-methyl-2,4,5-trifluorobenzoic acid amide
EINECS	Contact for details

Quality Control

Our 2,4,5-Trifluoro-n-Methoxy-n-Methylbenzamide is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, supporting its use in regulated research and development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere to prevent degradation. Keep away from incompatible materials such as strong bases and fluorides.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.