Description

Methyl 5-Fluorobenzo[B]Thiophene-3-Carboxylate is a high-purity fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key precursor for the development of novel pharmaceutical intermediates and agrochemicals, enabling the introduction of the benzo[b]thiophene scaffold with strategic fluorine substitution. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating new active molecules.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing potential drug candidates, particularly in kinase inhibitor and CNS-active compound research.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that leverage the fluorinated benzo[b]thiophene core.
• Material Science Precursor: Serves as a monomer or functional unit in the synthesis of organic semiconductors and specialty polymers.
• Chemical Biology Probe: Employed in the design of molecular probes and fluorescent tags for biological imaging and assay development.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for bespoke synthesis projects and library production.

Basic Information

Product Name	Methyl 5-Fluorobenzo[B]Thiophene-3-Carboxylate
CAS No.	1187931-42-5
Molecular Formula	C10H7FO2S
Molecular Weight	210.22 g/mol
Synonyms	5-Fluorobenzo[b]thiophene-3-carboxylic acid methyl ester; Methyl 5-fluorobenzo[b]thiophene-3-carboxylate; 5-Fluoro-1-benzothiophene-3-carboxylic acid methyl ester; 3-Methoxycarbonyl-5-fluorobenzo[b]thiophene; 5-Fluoro-benzo[b]thiophene-3-carboxylic acid methyl ester; MFBTC; 1187931-42-5
EINECS	Contact for details

Quality Control

Our Methyl 5-Fluorobenzo[B]Thiophene-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to cGMP principles and ISO standards ensures reliable supply for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. Handle and store in accordance with all applicable regulations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.