Description

2-Fluoro-3-(Methylsulfonyl)Benzoic Acid is a high-value fluorinated benzoic acid derivative featuring a methylsulfonyl substituent, making it a versatile and critical building block in advanced organic synthesis. This compound is prized for its role in modulating the physicochemical properties of target molecules, particularly in the development of active pharmaceutical ingredients (APIs). It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of novel drug candidates, especially in kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, where the fluorine and sulfone groups contribute to efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in catalytic systems and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic materials with specific electronic properties.
• Chemical Biology Probes: Utilized as a building block for synthesizing molecular probes to study biological pathways and enzyme functions.

Basic Information

Product Name	2-Fluoro-3-(Methylsulfonyl)Benzoic Acid
CAS No.	1186663-47-7
Molecular Formula	C8H7FO4S
Molecular Weight	218.20 g/mol
Synonyms	3-(Methylsulfonyl)-2-fluorobenzoic Acid; 2-Fluoro-3-methanesulfonylbenzoic Acid; Benzoic acid, 2-fluoro-3-(methylsulfonyl)-; 2-Fluoro-3-(methylsulfonyl)benzoic acid; 1186663-47-7; 2-Fluoro-3-mesylbenzoic acid
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-3-(Methylsulfonyl)Benzoic Acid is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our products are supported by a detailed Certificate of Analysis (COA) that includes data from HPLC, NMR, and mass spectrometry. We adhere to cGMP guidelines where applicable to meet the stringent requirements of our global clientele in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and desiccated to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.