Description

2-Fluoro-4-(4-Methylphenyl)Benzoic Acid is a high-value fluorinated aromatic carboxylic acid derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both a fluorine atom and a biaryl system, makes it an essential intermediate for creating compounds with tailored electronic and steric properties. This product is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system and metabolic diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated liquid crystal molecules and electron-transport materials in organic light-emitting diodes (OLEDs).
• Polymer Modification: Incorporated as a monomer or additive to impart specific thermal, chemical, or surface properties to high-performance engineering plastics.
• Chemical Research & Development: Employed in academic and industrial R&D for studying structure-activity relationships and developing new synthetic methodologies involving fluorinated aromatics.
• Coordination Chemistry Ligand: The carboxylic acid and aryl fluoride groups allow it to act as a versatile ligand for metal-organic frameworks (MOFs) and catalysts.

Basic Information

Product Name	2-Fluoro-4-(4-Methylphenyl)Benzoic Acid
CAS No.	1184212-56-3
Molecular Formula	C14H11FO2
Molecular Weight	230.24 g/mol
Synonyms	2-Fluoro-4-(p-tolyl)benzoic Acid; 4'-Methyl-[1,1'-biphenyl]-2-carboxylic Acid, 2'-Fluoro-; 2-Fluoro-4-(4-methylphenyl)benzoic acid; [1,1'-Biphenyl]-2-carboxylic acid, 2'-fluoro-4'-methyl-; 2'-Fluoro-4'-methylbiphenyl-2-carboxylic acid; 2-Fluoro-4-(p-methylphenyl)benzoic acid; 4-(4-Methylphenyl)-2-fluorobenzoic Acid
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-(4-Methylphenyl)Benzoic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your research or production specifications. Custom purity grades and analytical packages are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Standard Grade)
Purity (HPLC)	≥99.0% (High Purity Grade)
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.