Description

2-Fluoro-5-(2-Oxo-Pyrrolidin-1-Yl)-Benzoic Acid is a high-value fluorinated benzoic acid derivative featuring a pyrrolidinone moiety, making it a critical building block in modern synthetic chemistry. This compound is essential for researchers and manufacturers requiring precise molecular architecture for advanced material and pharmaceutical development. It is primarily utilized in the synthesis of active pharmaceutical ingredients (APIs), agrochemicals, and functional materials where its unique fluorinated heterocyclic structure imparts desirable biological and physical properties.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the fluorine atom enhances bioavailability and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of monomers for specialty polymers and liquid crystals with tailored electronic properties.
• Chemical Biology Probes: Utilized as a scaffold for developing fluorescent tags and molecular probes for diagnostic applications.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthetic routes and scale-up projects.

Basic Information

Product Name	2-Fluoro-5-(2-Oxo-Pyrrolidin-1-Yl)-Benzoic Acid
CAS No.	1184109-81-6
Molecular Formula	C11H10FNO3
Molecular Weight	223.20 g/mol
Synonyms	1-(3-Fluoro-4-carboxyphenyl)pyrrolidin-2-one; 5-Fluoro-2-(2-oxo-1-pyrrolidinyl)benzoic Acid; 2-Fluoro-5-(2-oxo-1-pyrrolidinyl)benzoic Acid; Benzoic acid, 2-fluoro-5-(2-oxo-1-pyrrolidinyl)-; 1184109-81-6; 2-Fluoro-5-(2-oxopyrrolidin-1-yl)benzoic acid
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-(2-Oxo-Pyrrolidin-1-Yl)-Benzoic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and pre-clinical development phases.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.