Description

5-(3-Cyanophenyl)-2-Fluorobenzoic Acid is a high-purity, multi-functional aromatic building block designed for advanced synthetic chemistry. This compound is valued for its unique molecular architecture, which combines a fluorinated benzoic acid core with a cyanophenyl substituent, enabling precise structural modifications in complex molecules. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Research: Serves as a critical scaffold for developing new herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Ligand Synthesis: Used in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs) in material science.
• Fluorinated Compound Library: An essential building block for creating diverse fluorinated compound libraries for high-throughput screening in drug discovery.
• Polymer Modification: Employed to introduce fluorinated and cyano-functionalized aromatic units into polymer backbones to alter thermal and chemical resistance properties.
• Academic & Contract Research: Supplied to universities and CROs (Contract Research Organizations) for fundamental research in organic methodology and medicinal chemistry.

Basic Information

Product Name	5-(3-Cyanophenyl)-2-Fluorobenzoic Acid
CAS No.	1183926-58-0
Molecular Formula	C14H8FNO2
Molecular Weight	241.22 g/mol
Synonyms	2-Fluoro-5-(3-cyanophenyl)benzoic Acid; 3-(2-Fluoro-5-carboxyphenyl)benzonitrile; 5-(3-Cyanophenyl)-2-fluorobenzoic acid; [1,1'-Biphenyl]-3-carbonitrile, 2'-fluoro-5'-carboxy-; 2'-Fluoro-5'-carboxy[1,1'-biphenyl]-3-carbonitrile
EINECS	Contact for details

Quality Control

Our 5-(3-Cyanophenyl)-2-Fluorobenzoic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and KF titration for moisture content, to ensure it meets the stringent requirements of research and process development. Certificates of Analysis (COA) with detailed chromatographic data are provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the original container tightly sealed under an inert atmosphere if possible to maintain long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.