Description

2-Fluoro-5-(4-Methylphenyl)Benzoic Acid is a high-value fluorinated aromatic carboxylic acid building block. This compound matters for its role as a critical intermediate in the synthesis of advanced pharmaceutical agents and functional materials. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of novel herbicides and fungicides, where the fluorine atom and biphenyl core enhance biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated mesogens and electron-transport materials in display and lighting technologies.
• Polymer Modification: Incorporated as a monomer or additive to impart specific thermal, optical, or chemical resistance properties to high-performance polymers.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions (e.g., Suzuki, Heck) and esterification/amidation processes to introduce fluorinated biphenyl carboxylic acid motifs.
• Chemical Research & Development: Essential for medicinal chemistry programs and material science research exploring structure-activity relationships (SAR).

Basic Information

Product Name	2-Fluoro-5-(4-Methylphenyl)Benzoic Acid
CAS No.	1183641-87-3
Molecular Formula	C14H11FO2
Molecular Weight	230.24 g/mol
Synonyms	2-Fluoro-5-p-tolylbenzoic Acid; 5-(4-Methylphenyl)-2-fluorobenzoic Acid; [1,1'-Biphenyl]-2-carboxylic Acid, 2'-Fluoro-5'-methyl-; 2'-Fluoro-5'-methyl[1,1'-biphenyl]-2-carboxylic Acid; 2-Fluoro-5-(4-methylphenyl)benzoic acid; 2-Fluoro-5-(p-tolyl)benzoic Acid
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-(4-Methylphenyl)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and production. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat sources and incompatible materials. The container should be kept tightly sealed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.