Description

3-(4-Chlorophenyl)-4-Fluorobenzoic Acid is a high-purity fluorinated aromatic carboxylic acid derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique bifunctional structure, which allows for selective derivatization at both the carboxylic acid and halogenated aromatic sites. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and fungicides, leveraging the bioactivity of the fluorinated chlorophenyl moiety.
• Liquid Crystal & OLED Materials: Serves as a building block for advanced electronic materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs), due to its stable aromatic core.
• Polymer Chemistry: Acts as a monomer or cross-linking agent for creating specialty polymers with enhanced thermal stability and chemical resistance.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D for exploring new coupling reactions and creating complex molecular architectures.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Product Name	3-(4-Chlorophenyl)-4-Fluorobenzoic Acid
CAS No.	1181639-60-0
Molecular Formula	C13H8ClFO2
Molecular Weight	250.65 g/mol
Synonyms	4-Fluoro-3-(4-chlorophenyl)benzoic Acid; 3-(p-Chlorophenyl)-4-fluorobenzoic Acid; 4-Fluoro-3-(4'-chlorophenyl)benzoic Acid; Benzoic acid, 3-(4-chlorophenyl)-4-fluoro-; 1181639-60-0; 3-(4-Chlorophenyl)-4-fluorobenzoic acid; 4-Fluoro-3-(4-chlorophenyl)benzoic acid
EINECS	Contact for details

Quality Control

Every batch of 3-(4-Chlorophenyl)-4-Fluorobenzoic Acid is manufactured under a strict quality management system and undergoes rigorous analytical testing to ensure consistency and purity. Our standard quality commitment includes comprehensive testing via HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.