Description

5'-Fluoro-2'-Methyl-[1,1'-Biphenyl]-4-Carboxylic Acid is a high-purity biphenyl carboxylic acid derivative, serving as a critical pharmaceutical intermediate and organic building block for advanced synthesis. Its unique structure, featuring fluorine and methyl substituents, makes it invaluable for modulating the biological activity and physicochemical properties of target molecules. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery and development.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for non-steroidal anti-inflammatory drugs (NSAIDs) and other small molecule therapeutics.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Ligand Synthesis: Building block for creating complex ligands used in catalysis and material science applications.
• Organic Electronic Materials: Potential monomer or intermediate for the development of advanced organic semiconductors and functional polymers.
• Agrochemical Research: Intermediate in the development of novel herbicides and pesticides, leveraging the biphenyl core structure.
• Chemical Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	5'-Fluoro-2'-Methyl-[1,1'-Biphenyl]-4-Carboxylic Acid
CAS No.	1179797-95-5
Molecular Formula	C14H11FO2
Molecular Weight	230.24 g/mol
Synonyms	4'-Fluoro-2'-Methylbiphenyl-4-carboxylic Acid; [1,1'-Biphenyl]-4-carboxylic Acid, 5'-Fluoro-2'-Methyl-; 2-Methyl-5-fluorobiphenyl-4-carboxylic Acid; 5-Fluoro-2-Methyl-4-biphenylcarboxylic Acid; 4-Carboxy-5'-fluoro-2'-methylbiphenyl; 5'-Fluoro-2'-methylbiphenyl-4-carboxylic acid; Biphenyl-4-carboxylic acid, 5'-fluoro-2'-methyl- derivative
EINECS	Contact for details

Quality Control

Our 5'-Fluoro-2'-Methyl-[1,1'-Biphenyl]-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment. We support cGMP and ISO compliant production for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.