Description

2-Fluoro-5-(4-Trifluoromethylphenyl)Benzoic Acid is a high-value fluorinated aromatic carboxylic acid derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and trifluoromethyl substituents, is engineered to impart desirable properties such as enhanced metabolic stability, lipophilicity, and bioavailability in target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in oncology, CNS, and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine motifs improve efficacy and environmental profile.
• Liquid Crystal Materials: Serves as a precursor for fluorinated liquid crystal compounds used in advanced display technologies.
• Organic Electronic Materials: Employed in the synthesis of materials for organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Research & Development: A versatile building block for exploring new chemical entities and reaction pathways in medicinal and synthetic chemistry.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the scale-up and production of client-specific target molecules.

Basic Information

Product Name	2-Fluoro-5-(4-Trifluoromethylphenyl)Benzoic Acid
CAS No.	1179671-81-8
Molecular Formula	C14H8F4O2
Molecular Weight	284.21 g/mol
Synonyms	2-Fluoro-5-[4-(trifluoromethyl)phenyl]benzoic Acid; [2-Fluoro-5-(4-trifluoromethylphenyl)]benzoic Acid; 5-(4-(Trifluoromethyl)phenyl)-2-fluorobenzoic Acid; Benzoic acid, 2-fluoro-5-[4-(trifluoromethyl)phenyl]-; α,α,α-Trifluoro-4'-(5-carboxy-2-fluorophenyl)toluene
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-5-(4-Trifluoromethylphenyl)Benzoic Acid is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and physical characteristics. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The container should be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.