Description

2-Fluoro-5-(4-Fluoro-2-Methylphenyl)Benzoic Acid is a high-value, multi-fluorinated aromatic carboxylic acid building block essential for advanced organic synthesis. This compound matters because its unique bifluoro-substituted biphenyl structure provides a versatile scaffold for constructing complex molecules with tailored electronic and steric properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for applications such as medicinal chemistry and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the production of fluorinated liquid crystals for advanced display technologies.
• Organic Electronic Materials: Employed in the synthesis of organic semiconductors and charge-transport materials for OLEDs and photovoltaic cells.
• Chemical Research: Acts as a versatile synthon in academic and industrial research for Suzuki-Miyaura and other cross-coupling reactions to create novel biphenyl derivatives.
• Complex Ligand Synthesis: Utilized for constructing specialized ligands in catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	2-Fluoro-5-(4-Fluoro-2-Methylphenyl)Benzoic Acid
CAS No.	1178482-85-3
Molecular Formula	C14H10F2O2
Molecular Weight	248.23 g/mol
Synonyms	5-(4-Fluoro-2-methylphenyl)-2-fluorobenzoic acid; 2'-Fluoro-4-fluoro-2-methyl-[1,1'-biphenyl]-5-carboxylic acid; [1,1'-Biphenyl]-5-carboxylic acid, 2'-fluoro-4-fluoro-2-methyl-; 2-Fluoro-5-(4-fluoro-2-methylphenyl)benzoic acid; 2'-Fluoro-4-fluoro-2-methylbiphenyl-5-carboxylic acid
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch of 2-Fluoro-5-(4-Fluoro-2-Methylphenyl)Benzoic Acid is analyzed using advanced techniques like HPLC, GC, and NMR to verify identity, purity, and impurity profiles. We adhere to strict in-house specifications designed to meet the demanding requirements of pharmaceutical R&D. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single unknown impurity	≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.