Description

2-Fluoro-5-Methylbiphenyl-3-Carboxylic Acid is a high-purity fluorinated biphenyl derivative that serves as a critical advanced intermediate in modern synthetic chemistry. Its value lies in its unique molecular scaffold, which combines a carboxylic acid functional group with fluorine and methyl substituents, enabling precise structural modifications for performance-driven applications. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries seeking to develop novel active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atom can improve metabolic stability and bioavailability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated compounds used in electronic displays and organic light-emitting diodes (OLEDs) due to its potential influence on charge transport and molecular alignment.
• Organic Synthesis & Catalysis: Employed as a versatile synthon in cross-coupling reactions, Suzuki-Miyaura couplings, and other metal-catalyzed transformations to construct complex biaryl systems.
• Material Science Research: Investigated for the development of novel polymers, ligands for metal-organic frameworks (MOFs), and specialty chemicals with tailored electronic properties.

Basic Information

Product Name	2-Fluoro-5-Methylbiphenyl-3-Carboxylic Acid
CAS No.	1178458-04-2
Molecular Formula	C14H11FO2
Molecular Weight	230.24 g/mol
Synonyms	3'-Fluoro-5'-methyl-[1,1'-biphenyl]-3-carboxylic acid; 2-Fluoro-5-methyl-3-biphenylcarboxylic acid; [1,1'-Biphenyl]-3-carboxylic acid, 3'-fluoro-5'-methyl-; 3-(3-Fluoro-5-methylphenyl)benzoic acid; 2-Fluoro-5-methylbiphenyl-3-carboxylic acid; 5-Methyl-2-fluorobiphenyl-3-carboxylic Acid
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-Methylbiphenyl-3-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) for each lot, supporting your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.