Description

2-Fluoro-4-Oxazolecarboxylic Acid is a high-value fluorinated heterocyclic building block essential for modern synthetic chemistry. This compound serves as a critical intermediate in the development of novel active pharmaceutical ingredients (APIs) and advanced agrochemicals, enabling the introduction of fluorine to enhance metabolic stability and bioavailability. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of fluorinated drug candidates, particularly in oncology, antiviral, and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides where the fluorine atom improves efficacy and environmental profile.
• Material Science: Serves as a precursor for advanced polymers and liquid crystals with tailored electronic and optical properties.
• Chemical Biology: Employed as a probe or labeling reagent in medicinal chemistry and biochemical research for structure-activity relationship (SAR) studies.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs engaged in custom synthesis and process development.

Basic Information

Product Name	2-Fluoro-4-Oxazolecarboxylic Acid
CAS No.	1167056-76-9
Molecular Formula	C4H2FNO3
Molecular Weight	131.06 g/mol
Synonyms	2-Fluoro-1,3-oxazole-4-carboxylic acid; 4-Oxazolecarboxylic acid, 2-fluoro-; 2-Fluorooxazole-4-carboxylic acid; 2-Fluoro-4-carboxyoxazole; 2-Fluoro-oxazole-4-carboxylic acid; 1167056-76-9; 2-Fluoro-4-oxazolecarboxylic acid
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-Oxazolecarboxylic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) for all shipments. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.