Description

2,4-Difluoro-5-Formylbenzoic Acid CAS NO 1162674-68-1 is a high-value, multi-functional aromatic building block characterized by its difluoro-substituted benzoic acid core and a reactive formyl group. This unique structure makes it a critical intermediate for synthesizing complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought after by research chemists and process development scientists for constructing active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in kinase inhibitor and anti-cancer agent research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, where the fluorine atoms enhance biological activity and stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated aromatic cores in electronic and display materials.
• Polymer Modification: Functional monomer for introducing fluorine and carboxylic acid groups into specialty polymers to alter surface properties and chemical resistance.
• Organic Synthesis & Research: Versatile reagent for Suzuki-Miyaura and other cross-coupling reactions, as well as for introducing aldehyde functionality into complex molecules.
• Coordination Chemistry: Potential ligand for metal-organic frameworks (MOFs) and catalysts due to its carboxylic acid and aldehyde groups.

Basic Information

Product Name	2,4-Difluoro-5-Formylbenzoic Acid
CAS No.	1162674-68-1
Molecular Formula	C8H4F2O3
Molecular Weight	186.11 g/mol
Synonyms	5-Formyl-2,4-difluorobenzoic Acid; 2,4-Difluoro-5-formylbenzoic Acid; 2,4-Difluorobenzaldehyde-5-carboxylic Acid; Benzoic acid, 2,4-difluoro-5-formyl-; 5-Carboxy-2,4-difluorobenzaldehyde
EINECS	Contact for details

Quality Control

Our 2,4-Difluoro-5-Formylbenzoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and KF for moisture content, to ensure it meets the high standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, and custom purity grades (e.g., >98%, >99%) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound may be light-sensitive and hygroscopic; handle and store under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.