Description

Methyl 3-Bromo-4-Chloro-5-Fluorobenzoate is a high-purity, multi-halogenated benzoate ester serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile, functionalized aromatic core for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for research chemists and process development scientists in fine chemical, pharmaceutical, and agrochemical industries who require reliable, high-quality intermediates for drug discovery and active ingredient development.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing complex halogenated aromatic systems.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides where the specific halogen pattern influences bioactivity.
• Liquid Crystal & OLED Material Research: Used in the development of advanced electronic materials and organic light-emitting diodes (OLEDs) due to its halogen-substituted aromatic structure.
• Cross-Coupling Reactions: Serves as a substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Functional Group Transformation: The methyl ester group allows for further transformations, including hydrolysis to the corresponding acid or reduction to the alcohol.
• Chemical Research & Development: A valuable tool for medicinal chemistry and process chemistry in exploring new chemical entities and optimizing synthetic routes.

Basic Information

Product Name	Methyl 3-Bromo-4-Chloro-5-Fluorobenzoate
CAS No.	1160574-62-8
Molecular Formula	C8H5BrClFO2
Molecular Weight	267.48 g/mol
Synonyms	3-Bromo-4-chloro-5-fluorobenzoic acid methyl ester; Methyl 3-bromo-4-chloro-5-fluorobenzoate; Benzoic acid, 3-bromo-4-chloro-5-fluoro-, methyl ester; 3-Bromo-4-chloro-5-fluorobenzoic acid, methyl ester; Methyl 3-bromo-4-chloro-5-fluorobenzoate (CAS 1160574-62-8)
EINECS	Contact for details

Quality Control

Our Methyl 3-Bromo-4-Chloro-5-Fluorobenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliable supply for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Melting Point	Contact for details
Heavy Metals	<10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.