Description

5-Fluoro-2-(1H-Pyrazol-1-Yl)Benzoic Acid is a high-value fluorinated heterocyclic building block that combines a benzoic acid core with a pyrazole moiety. This compound is critical for medicinal chemistry research and development, serving as a versatile intermediate for constructing novel active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of targeted small molecule therapeutics, particularly in oncology and CNS drug discovery.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, especially kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its fluorinated aromatic and heterocyclic structure.
• Agrochemical Synthesis: Serves as a building block for advanced crop protection agents, leveraging the biological activity of the pyrazole ring.
• Material Science Precursor: Potential monomer or functionalizing agent for specialty polymers and advanced organic materials.
• Chemical Biology Probes: Utilized in the design of molecular probes and diagnostic agents for biochemical research.

Basic Information

Product Name	5-Fluoro-2-(1H-Pyrazol-1-Yl)Benzoic Acid
CAS No.	1152964-04-9
Molecular Formula	C10H7FN2O2
Molecular Weight	206.18 g/mol
Synonyms	5-Fluoro-2-(1H-pyrazol-1-yl)benzoic acid; 2-(1H-Pyrazol-1-yl)-5-fluorobenzoic Acid; 5-Fluoro-2-(1H-pyrazol-1-yl)benzoic acid; Benzoic acid, 5-fluoro-2-(1H-pyrazol-1-yl)-; 1152964-04-9; 5-Fluoro-2-(pyrazol-1-yl)benzoic acid; 5-Fluoro-2-(1-pyrazolyl)benzoic Acid
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-(1H-Pyrazol-1-Yl)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for research-grade chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.