Description

4-(3,5-Dimethyl-1H-Pyrazol-1-Yl)-3-Fluorobenzoic Acid is a high-value, multi-functional heterocyclic benzoic acid derivative that serves as a critical building block in advanced organic synthesis. Its molecular architecture, featuring a fluorinated benzoic acid core linked to a dimethylpyrazole moiety, makes it an essential intermediate for developing novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors, anti-inflammatory agents, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the synthesis of advanced herbicides, fungicides, and insecticides, where the fluorine atom and heterocyclic system can enhance bioavailability and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis, useful in asymmetric synthesis and material science.
• Chemical Biology Research: Employed as a molecular probe or a tagging reagent in proteomics and bio-conjugation studies due to its reactive carboxylic acid group and stable heterocycle.
• Material Science Precursor: Can be utilized in the synthesis of functionalized polymers, liquid crystals, or organic electronic materials requiring specific fluorinated aromatic components.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring this specific fluoropyrazole-benzoic acid scaffold.

Basic Information

Product Name	4-(3,5-Dimethyl-1H-Pyrazol-1-Yl)-3-Fluorobenzoic Acid
CAS No.	1152868-20-6
Molecular Formula	C12H11FN2O2
Molecular Weight	234.23 g/mol
Synonyms	3-Fluoro-4-(3,5-dimethyl-1H-pyrazol-1-yl)benzoic Acid; 4-(3,5-Dimethylpyrazol-1-yl)-3-fluorobenzoic Acid; 1-(4-Carboxy-2-fluorophenyl)-3,5-dimethyl-1H-pyrazole; 1152868-20-6; Benzoic acid, 3-fluoro-4-(3,5-dimethyl-1H-pyrazol-1-yl)-
EINECS	Contact for details

Quality Control

Our 4-(3,5-Dimethyl-1H-Pyrazol-1-Yl)-3-Fluorobenzoic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, NMR and IR for structural confirmation, and KF titration for moisture content. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support cGMP standards for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.