Description

Methyl5-Bromo-2,3-Difluorobenzoate CAS NO 1150163-69-1 is a high-purity, multi-functional aromatic ester building block, specifically engineered for advanced organic synthesis. Its core value lies in providing a versatile and reactive scaffold for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials who require reliable, high-quality intermediates to ensure successful downstream reactions and final product integrity.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those containing difluorinated aromatic systems for improved metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the bromo and difluoro substituents contribute to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and polymers requiring specific halogenated aromatic components.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.
• Academic and R&D Laboratories: Used in methodological studies and the exploration of new fluorination and cross-coupling reaction pathways.

Basic Information

Product Name	Methyl5-Bromo-2,3-Difluorobenzoate
CAS No.	1150163-69-1
Molecular Formula	C8H5BrF2O2
Molecular Weight	251.03 g/mol
Synonyms	Methyl 5-bromo-2,3-difluorobenzoate; 5-Bromo-2,3-difluorobenzoic acid methyl ester; Benzoic acid, 5-bromo-2,3-difluoro-, methyl ester; Methyl 5-bromo-2,3-difluorobenzenecarboxylate; 2,3-Difluoro-5-bromobenzoic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl5-Bromo-2,3-Difluorobenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates, ensuring reliability for your most critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive and easily oxidized; for long-term storage, consider maintaining under an inert atmosphere (e.g., nitrogen or argon) to preserve stability and prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.