Description

3-(Trifluoromethyl)Quinoxaline-2-Carboxylic Acid is a high-value, multi-functional heterocyclic building block. This compound is critical for the synthesis of advanced materials and active pharmaceutical ingredients (APIs) due to its unique trifluoromethylated quinoxaline core. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel compounds with enhanced biological activity and physical properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the trifluoromethyl group can improve metabolic stability and lipophilicity.
• Material Science Research: Serves as a precursor for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic light-emitting diodes (OLEDs).
• Chemical Biology Probes: Employed in the design and synthesis of fluorescent tags or molecular probes for studying biological processes.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring complex, fluorinated heterocyclic architectures.

Basic Information

Product Name	3-(Trifluoromethyl)Quinoxaline-2-Carboxylic Acid
CAS No.	1142190-60-0
Molecular Formula	C11H5F3N2O2
Molecular Weight	254.17 g/mol
Synonyms	2-Quinoxalinecarboxylic acid, 3-(trifluoromethyl)-; 3-(Trifluoromethyl)-2-quinoxalinecarboxylic acid; Quinoxaline-2-carboxylic acid, 3-(trifluoromethyl)-; 3-Trifluoromethylquinoxaline-2-carboxylic acid; TFQCA; 1142190-60-0
EINECS	Contact for details

Quality Control

Our 3-(Trifluoromethyl)Quinoxaline-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.