Description

3-Fluoro-5-Methoxy-4-Nitrobenzoic Acid is a high-purity, multi-functional aromatic building block designed for advanced chemical synthesis. This compound is valued for its unique substitution pattern, which introduces both electron-withdrawing and electron-donating groups onto the benzoic acid core, enabling precise molecular modifications. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for molecules requiring a fluorinated, nitro-substituted aromatic scaffold.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the fluorine atom and nitro group enhance biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in catalytic systems and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the creation of novel polymers, liquid crystals, and organic electronic materials with tailored properties.
• Fluorine Chemistry Studies: An important substrate for investigating fluorination reactions and the effects of fluorine substitution on aromatic systems.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring this precise chemical architecture.

Basic Information

Product Name	3-Fluoro-5-Methoxy-4-Nitrobenzoic Acid
CAS No.	1137869-93-2
Molecular Formula	C8H6FNO5
Molecular Weight	215.14 g/mol
Synonyms	4-Nitro-3-fluoro-5-methoxybenzoic acid; 3-Fluoro-5-methoxy-4-nitrobenzoic acid; Benzoic acid, 3-fluoro-5-methoxy-4-nitro-; 1137869-93-2; 3-Fluoro-4-nitro-5-methoxybenzoic acid; 5-Methoxy-3-fluoro-4-nitrobenzoic acid
EINECS	Contact for details

Quality Control

Every batch of 3-Fluoro-5-Methoxy-4-Nitrobenzoic Acid is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.