Description

3-Iodo-4-(2,2,2-trifluoroethoxy)benzoic acid is a high-value, multi-functional aromatic building block featuring both a carboxylic acid and a trifluoroethoxy substituent. This compound is essential for medicinal chemistry and advanced materials research, where its unique halogenated structure enables precise molecular modifications. It is primarily sought by pharmaceutical R&D teams and fine chemical manufacturers for developing novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of potential drug candidates, particularly for targeted therapies.
• Agrochemical Research: Used in developing advanced herbicides and pesticides due to the bioactivity of the trifluoroethoxy group.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorine-containing compounds used in electronic display technologies.
• Organic Synthesis Building Block: The iodine and carboxylic acid groups provide versatile sites for cross-coupling reactions and further derivatization.
• PET (Positron Emission Tomography) Tracer Development: The iodine atom offers a potential site for radioisotope labeling for diagnostic imaging agents.
• Polymer Modification: Can be incorporated into polymer chains to impart specific chemical resistance or surface properties.

Basic Information

Product Name	3-Iodo-4-(2,2,2-trifluoroethoxy)benzoic Acid
CAS No.	1131614-66-8
Molecular Formula	C9H6F3IO3
Molecular Weight	346.04 g/mol
Synonyms	4-(2,2,2-Trifluoroethoxy)-3-iodobenzoic Acid; 3-Iodo-4-(2,2,2-trifluoroethoxy)benzoic Acid; Benzoic acid, 3-iodo-4-(2,2,2-trifluoroethoxy)-; 1131614-66-8; 3-Iodo-4-trifluoroethoxybenzoic Acid
EINECS	Contact for details

Quality Control

Our production of 3-Iodo-4-(2,2,2-trifluoroethoxy)benzoic acid adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and scale-up applications. Each lot is analyzed using advanced techniques including HPLC, NMR, and MS to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.