Description

4-Amino-2-Chloro-3-Fluorobenzoic Acid is a high-purity, multi-functional aromatic building block essential for advanced organic synthesis. This compound matters as a key intermediate in the development of complex molecules, offering precise substitution patterns for structure-activity relationship (SAR) studies. It is primarily needed by pharmaceutical, agrochemical, and advanced material research organizations for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and pesticides, where the fluorine and chlorine substituents enhance biological activity and environmental stability.
• Material Science Research: Serves as a precursor for functional polymers, liquid crystals, and organic electronic materials due to its aromatic core and halogen/amino functional groups.
• Chemical Biology & Proteomics: Employed as a specialty reagent for designing molecular probes, enzyme inhibitors, and fluorescent tags for biochemical research.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	4-Amino-2-Chloro-3-Fluorobenzoic Acid
CAS No.	1124214-25-0
Molecular Formula	C7H5ClFNO2
Molecular Weight	189.57 g/mol
Synonyms	2-Chloro-3-fluoro-4-aminobenzoic acid; Benzoic acid, 4-amino-2-chloro-3-fluoro-; 4-Amino-2-chloro-3-fluorobenzoic acid; 2-Chloro-3-fluoro-4-aminobenzoic acid; 4-Amino-2-chloro-3-fluoro-benzoic acid; 1124214-25-0; 4-Amino-2-chloro-3-fluorobenzoic acid CAS 1124214-25-0
EINECS	Contact for details

Quality Control

Our 4-Amino-2-Chloro-3-Fluorobenzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.