Description

Methyl 4-Amino-3-Bromo-5-Fluorobenzoate is a high-purity, multi-functional aromatic ester building block designed for advanced organic synthesis. This compound is critical for research and development in the pharmaceutical and agrochemical sectors, where precise molecular construction is paramount. It serves as a key intermediate for medicinal chemists and process development scientists seeking to introduce halogenated aniline motifs into complex target molecules.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors, anticancer agents, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging the fluorine and bromine substituents for enhanced biological activity and environmental stability.
• Material Science Research: Serves as a monomer or precursor for the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a scaffold or linker in the design of molecular probes, activity-based probes (ABPs), and other tools for studying biological systems.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences industry.

Basic Information

Product Name	Methyl 4-Amino-3-Bromo-5-Fluorobenzoate
CAS No.	1123171-91-4
Molecular Formula	C8H7BrFNO2
Molecular Weight	248.05 g/mol
Synonyms	4-Amino-3-bromo-5-fluorobenzoic acid methyl ester; Methyl 4-amino-3-bromo-5-fluorobenzoate; Benzoic acid, 4-amino-3-bromo-5-fluoro-, methyl ester; 3-Bromo-5-fluoro-4-aminobenzoic acid methyl ester; Methyl 3-bromo-5-fluoro-4-aminobenzoate; 4-Amino-3-bromo-5-fluorobenzoate methyl ester; Methyl ester of 4-amino-3-bromo-5-fluorobenzoic acid
EINECS	Contact for details

Quality Control

Our Methyl 4-Amino-3-Bromo-5-Fluorobenzoate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. Certificates of Analysis (COA) are available for every batch, detailing all relevant specifications and test results to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.