Description

2-Amino-4-Fluoro-5-Hydroxy-Benzoic Acid Methyl Ester is a high-purity, multi-functional fluorinated benzoic acid derivative that serves as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring amino, fluoro, and hydroxy substituents, makes it a versatile intermediate for creating complex molecules with tailored properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to synthesize novel active ingredients and fine chemicals. Its reliable quality and consistent performance are paramount for ensuring the success of downstream applications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in the development of fluorinated active pharmaceutical ingredients (APIs) targeting various therapeutic areas.
• Agrochemical Synthesis: Used to construct advanced herbicide and pesticide molecules, where the fluorine atom can enhance biological activity, metabolic stability, and selectivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis and metal-catalyzed reactions.
• Material Science Research: Employed in the development of specialty polymers, liquid crystals, and organic electronic materials due to its functional group diversity.
• Fluorescent Probe and Dye Synthesis: Acts as a core structure for synthesizing advanced fluorescent markers and dyes used in bio-imaging and diagnostic applications.
• Academic and R&D Laboratories: A valuable reagent for methodological studies in organic chemistry, exploring new fluorination and functionalization reactions.

Basic Information

Product Name	2-Amino-4-Fluoro-5-Hydroxy-Benzoic Acid Methyl Ester
CAS No.	1113049-61-8
Molecular Formula	C8H8FNO3
Molecular Weight	185.15 g/mol
Synonyms	Methyl 2-Amino-4-Fluoro-5-Hydroxybenzoate; 2-Amino-4-Fluoro-5-Hydroxy Methyl Benzoate; Benzoic Acid, 2-Amino-4-Fluoro-5-Hydroxy-, Methyl Ester; 4-Fluoro-5-Hydroxyanthranilic Acid Methyl Ester; Methyl 4-Fluoro-5-Hydroxyanthranilate; 2-Amino-4-Fluoro-5-Hydroxybenzoic Acid, Methyl Ester; 1113049-61-8
EINECS	Contact for details

Quality Control

Our 2-Amino-4-Fluoro-5-Hydroxy-Benzoic Acid Methyl Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive quality assurance, with each lot accompanied by a detailed Certificate of Analysis (COA) that includes results for identity, purity, and impurity profiles. Our standard grade meets typical research and industrial requirements, and we can discuss custom specifications to align with your specific project needs, including compliance with relevant guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed after each use to minimize exposure to atmospheric moisture and light, which can affect product stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.