Description

4-Bromo-5-(Chlorosulfonyl)-2-Fluorobenzoic Acid is a high-purity, multifunctional aromatic building block designed for advanced synthetic chemistry. This compound is valued for its unique combination of reactive handles—bromine, chlorosulfonyl, fluorine, and carboxylic acid groups—enabling precise molecular construction. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of complex, biologically active molecules, including potential active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those requiring sulfonamide, sulfonyl chloride, or fluorinated aromatic motifs.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides where the fluorine atom and sulfonyl group enhance bioactivity and stability.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers, such as polyimides or sulfonated polymers for advanced materials.
• Chemical Biology Probes: Employed in the creation of molecular probes and tags for studying biological processes due to its reactive sites suitable for bioconjugation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific, multi-step synthetic routes.

Basic Information

Product Name	4-Bromo-5-(Chlorosulfonyl)-2-Fluorobenzoic Acid
CAS No.	1099186-78-3
Molecular Formula	C7H3BrClFO4S
Molecular Weight	317.52 g/mol
Synonyms	2-Fluoro-4-bromo-5-(chlorosulfonyl)benzoic acid; 4-Bromo-2-fluoro-5-sulfonylchloride-benzoic acid; 5-(Chlorosulfonyl)-4-bromo-2-fluorobenzoic acid; Benzoic acid, 4-bromo-5-(chlorosulfonyl)-2-fluoro-; 4-Bromo-5-chlorosulfonyl-2-fluorobenzoic acid; CAS 1099186-78-3
EINECS	Contact for details

Quality Control

Our 4-Bromo-5-(Chlorosulfonyl)-2-Fluorobenzoic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can provide material suitable for use under cGMP (current Good Manufacturing Practice) guidelines for pharmaceutical development upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.