Description

3-Amino-4-Difluoromethoxy-Benzoic Acid is a high-purity, multifunctional aromatic building block of significant interest in advanced organic synthesis. Its core value lies in the strategic combination of an amino group, a difluoromethoxy moiety, and a carboxylic acid functional group, enabling precise molecular modifications. This compound is primarily sought after by R&D and production chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients, where its unique fluorine-containing structure can enhance metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in oncology, CNS, and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the difluoromethoxy group can improve efficacy and environmental profile.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorine-containing aromatic compounds used in electronic display technologies.
• Advanced Polymer Modification: Incorporated into specialty polymers to impart specific chemical resistance, thermal stability, or surface properties.
• Complex Ligand & Catalyst Development: Utilized in organometallic chemistry for designing novel ligands in catalytic processes.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom chemical synthesis services catering to diverse R&D needs.

Basic Information

Product Name	3-Amino-4-Difluoromethoxy-Benzoic Acid
CAS No.	1096879-61-6
Molecular Formula	C8H7F2NO3
Molecular Weight	203.14 g/mol
Synonyms	4-(Difluoromethoxy)-3-aminobenzoic acid; 3-Amino-4-(difluoromethoxy)benzoic acid; Benzoic acid, 3-amino-4-(difluoromethoxy)-; 1096879-61-6; 4-Difluoromethoxy-3-aminobenzoic acid; 3-AADFBA
EINECS	Contact for details

Quality Control

Every batch of 3-Amino-4-Difluoromethoxy-Benzoic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by HPLC, NMR, and other relevant techniques.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.