Description

2-(2,5-Difluorophenyl)-2-Oxoacetic Acid is a high-purity, specialized fluorinated building block essential for advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecules with specific biological activity.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and pesticides, leveraging the difluorophenyl moiety for enhanced bioactivity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of advanced polymers and organic electronic materials where fluorinated aromatic units are required.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.

Basic Information

Item	Details
Product Name	2-(2,5-Difluorophenyl)-2-Oxoacetic Acid
CAS No.	1094294-16-2
Molecular Formula	C8H4F2O3
Molecular Weight	186.11 g/mol
Synonyms	2,5-Difluorobenzoylformic Acid; (2,5-Difluorophenyl)(oxo)acetic Acid; α-Oxo-2,5-difluorobenzeneacetic Acid; 2,5-Difluorophenylglyoxylic Acid; 2,5-Difluoromandelic Acid Ketone; 1094294-16-2; Difluorophenyl Oxoacetic Acid Derivative
EINECS	Contact for details

Quality Control

Every batch of 2-(2,5-Difluorophenyl)-2-Oxoacetic Acid is produced under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency meet the exacting standards required for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from direct light sources to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.