Description

2-(3-Fluorophenyl)-2-Hydroxypropanoic Acid is a high-purity fluorinated organic acid derivative, serving as a critical chiral building block and intermediate in advanced chemical synthesis. Its value lies in the precise introduction of a fluorine atom and a hydroxy acid moiety onto an aromatic system, enabling the fine-tuning of molecular properties for target applications. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced material sectors who require reliable, high-quality intermediates for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key chiral precursor for the synthesis of fluorinated active pharmaceutical ingredients (APIs), including potential non-steroidal anti-inflammatory drugs (NSAIDs) and other bioactive molecules.
• Agrochemical Synthesis: Building block for developing novel fluorinated herbicides, fungicides, and plant growth regulators, where the fluorine atom enhances bioavailability and stability.
• Ligand and Catalyst Development: Used in the preparation of chiral ligands for asymmetric catalysis, leveraging the hydroxy acid functionality for metal coordination.
• Advanced Material Research: Intermediate for synthesizing fluorinated monomers or additives aimed at modifying polymer properties like surface energy, chemical resistance, and optical characteristics.
• Chemical Biology Probes: Serves as a starting point for creating fluorinated probes and tags used in metabolic studies and imaging applications.
• Custom Synthesis and Process Development: A valuable substrate for contract research organizations (CROs) and process chemistry groups scaling up synthetic routes.

Basic Information

Product Name	2-(3-Fluorophenyl)-2-Hydroxypropanoic Acid
CAS No.	1083317-38-7
Molecular Formula	C9H9FO3
Molecular Weight	184.16 g/mol
Synonyms	2-Hydroxy-2-(3-fluorophenyl)propanoic Acid; α-Hydroxy-3-fluorophenylpropionic Acid; 3-Fluoro-α-hydroxybenzenepropanoic Acid; 2-(3-Fluorophenyl)lactic Acid (common name analogy); (±)-2-Hydroxy-2-(3-fluorophenyl)propanoic Acid; DL-2-(3-Fluorophenyl)-2-hydroxypropanoic Acid; 3-Fluorophenyl lactic acid derivative; 1083317-38-7 (CAS Index Name)
EINECS	Contact for details

Quality Control

Every batch of 2-(3-Fluorophenyl)-2-Hydroxypropanoic Acid is manufactured under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency meet the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Chiral Purity (if applicable)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.