Description

4-Fluoro-3-Phenylbenzoic Acid is a high-purity fluorinated aromatic carboxylic acid building block of significant importance in advanced organic synthesis. Its unique structure, featuring both a fluorine atom and a phenyl substituent on the benzoic acid core, makes it a versatile intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators, where the fluorine atom can enhance bioavailability and stability.
• Liquid Crystal & OLED Material Precursor: Serves as a critical starting material for synthesizing fluorinated aromatic compounds used in electronic displays and organic light-emitting diodes (OLEDs).
• Polymer Modification: Employed to introduce fluorine and aromatic groups into polymer chains, improving material properties like chemical resistance, thermal stability, and dielectric constant.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new reactions in medicinal chemistry and materials science.
• Ligand Synthesis for Catalysis: Used to prepare sophisticated ligands for transition metal catalysts, enabling more efficient and selective chemical transformations.

Basic Information

Product Name	4-Fluoro-3-Phenylbenzoic Acid
CAS No.	1082484-37-4
Molecular Formula	C13H9FO2
Molecular Weight	216.21 g/mol
Synonyms	3-Phenyl-4-fluorobenzoic Acid; 4-Fluoro-3-phenyl-benzoic Acid; 4-Fluoro-[1,1'-biphenyl]-3-carboxylic Acid; 3-Carboxy-4-fluorobiphenyl; 4-Fluoro-3-biphenylcarboxylic Acid; Benzoic acid, 4-fluoro-3-phenyl-; [1,1'-Biphenyl]-3-carboxylic acid, 4'-fluoro-
EINECS	Contact for details

Quality Control

Our 4-Fluoro-3-Phenylbenzoic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the stringent requirements of our clients in regulated industries. A detailed Certificate of Analysis (COA) is provided with each shipment, and custom purity grades are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.