Description

3-Amino-4-Fluoro-2-Methyl-Benzoic Acid Methyl Ester is a high-value fluorinated benzoic acid derivative that serves as a critical building block in advanced organic synthesis. Its molecular structure, featuring both amino and fluoro substituents, makes it an essential intermediate for constructing complex pharmacologically active molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Building block for developing advanced herbicides and pesticides with improved efficacy and selectivity.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Intermediate for creating fluorinated polymers and advanced organic electronic materials.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic and R&D: Utilized in university and corporate research laboratories for methodological studies and exploring new chemical entities.

Basic Information

Product Name	3-Amino-4-Fluoro-2-Methyl-Benzoic Acid Methyl Ester
CAS No.	1079993-18-2
Molecular Formula	C9H10FNO2
Molecular Weight	183.18 g/mol
Synonyms	Methyl 3-Amino-4-Fluoro-2-Methylbenzoate; 4-Fluoro-3-Amino-2-Methylbenzoic Acid Methyl Ester; 2-Methyl-3-Amino-4-Fluorobenzoic Acid Methyl Ester; Benzoic acid, 3-amino-4-fluoro-2-methyl-, methyl ester; Methyl 4-fluoro-3-amino-o-toluate
EINECS	Contact for details

Quality Control

Our production of 3-Amino-4-Fluoro-2-Methyl-Benzoic Acid Methyl Ester adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy. We provide full traceability and Certificates of Analysis (COA) are supplied with every shipment, detailing all critical quality attributes. Our quality system is designed to support cGMP and ICH guideline requirements for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.