Description

Methyl 6-Fluoro-2-Methyl-3-Nitrobenzoate is a high-purity fluorinated aromatic ester building block, essential for advanced organic synthesis. Its value lies in providing a versatile scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific fluorine and nitro functional groups into target structures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antimicrobials.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and insecticides where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Material Research: Serves as a building block for fluorinated organic electronic materials due to its aromatic core and specific substitution pattern.
• Chemical Biology & Proteomics: Employed in the design and synthesis of activity-based probes (ABPs) and molecular tags for studying enzyme function.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing complex, fluorinated target molecules for clients.

Basic Information

Product Name	Methyl 6-Fluoro-2-Methyl-3-Nitrobenzoate
CAS No.	1079992-97-4
Molecular Formula	C10H10FNO4
Molecular Weight	227.19 g/mol
Synonyms	Methyl 6-Fluoro-2-methyl-3-nitrobenzoate; 6-Fluoro-2-methyl-3-nitrobenzoic Acid Methyl Ester; Benzoic acid, 6-fluoro-2-methyl-3-nitro-, methyl ester; Methyl 2-Methyl-6-fluoro-3-nitrobenzoate; 3-Nitro-6-fluoro-2-methylbenzoic Acid Methyl Ester; 1079992-97-4
EINECS	Contact for details

Quality Control

Our Methyl 6-Fluoro-2-Methyl-3-Nitrobenzoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.