Description

Ethyl 4-Fluoro-2-Nitrobenzoate is a high-purity fluorinated aromatic ester derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both a nitro and a fluoro substituent, makes it a versatile intermediate for constructing complex pharmacophores and agrochemicals. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific functional groups into target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing fluorinated aromatic systems for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the nitro and fluoro groups contribute to biological activity.
• Liquid Crystal & OLED Material Research: Serves as a starting material for synthesizing fluorinated organic compounds used in electronic displays and optoelectronic devices.
• Dye & Pigment Manufacturing: Acts as an intermediate for producing specialized fluorinated dyes and colorants.
• Cross-Coupling Reactions: A valuable substrate in palladium-catalyzed reactions, such as Suzuki or Buchwald-Hartwig amination, for creating biaryl structures.
• Academic & Contract Research: Employed in research laboratories for method development and exploring new synthetic pathways in medicinal and organic chemistry.

Basic Information

Product Name	Ethyl 4-Fluoro-2-Nitrobenzoate
CAS No.	1072207-10-3
Molecular Formula	C9H8FNO4
Molecular Weight	213.16 g/mol
Synonyms	Benzoic acid, 4-fluoro-2-nitro-, ethyl ester; Ethyl 4-fluoro-2-nitrobenzoate; 4-Fluoro-2-nitrobenzoic acid ethyl ester; 2-Nitro-4-fluorobenzoic acid ethyl ester; Ethyl p-fluoro-o-nitrobenzoate; 1072207-10-3; Ethyl 4-fluoro-2-nitrobenzoate (CAS 1072207-10-3)
EINECS	Contact for details

Quality Control

Our Ethyl 4-Fluoro-2-Nitrobenzoate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis. A Certificate of Analysis (COA) is supplied with each batch, detailing all specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat sources and incompatible materials. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.