Description

3-Cyclopropyl-4-Fluorobenzoic Acid is a high-purity fluorinated benzoic acid derivative serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both cyclopropyl and fluorine substituents, provides valuable steric and electronic properties for modulating the activity of target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients with enhanced efficacy and selectivity.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorinated cyclopropyl moiety can improve metabolic stability and binding affinity.
• Ligand and Catalyst Development: Serves as a precursor for designing novel ligands in transition metal catalysis and organocatalysis, enabling new synthetic methodologies.
• Material Science Research: Employed in the synthesis of specialty polymers, liquid crystals, and organic electronic materials due to its ability to influence molecular packing and electronic characteristics.
• Chemical Biology Probes: Utilized as a building block for creating fluorescent tags, photoaffinity labels, and other molecular probes to study biological systems.

Basic Information

Product Name	3-Cyclopropyl-4-Fluorobenzoic Acid
CAS No.	1063733-86-7
Molecular Formula	C10H9FO2
Molecular Weight	180.18 g/mol
Synonyms	4-Fluoro-3-cyclopropylbenzoic Acid; 3-Cyclopropyl-4-fluorobenzoic Acid; Benzoic acid, 3-cyclopropyl-4-fluoro-; 1063733-86-7; 4-Fluoro-3-cyclopropyl-benzoic acid; 3-Cyclopropyl-4-fluoro-benzoic acid; 3-Cyclopropyl-4-fluorobenzoic acid (CAS 1063733-86-7)
EINECS	Contact for details

Quality Control

Our 3-Cyclopropyl-4-Fluorobenzoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with customer specifications and industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.