Description

4-Acetyl-3-Fluorobenzoic Acid Methyl Ester is a high-purity fluorinated aromatic ester building block of significant interest in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), liquid crystal materials, and novel agrochemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the construction of fluorinated drug candidates, including kinase inhibitors and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for display technologies.
• Organic Electronics: Employed in the development of organic semiconductors and charge-transport materials.
• Chemical Research: A valuable building block for academic and industrial research in medicinal chemistry and material science.
• Custom Synthesis: Used by contract research and manufacturing organizations (CROs/CMOs) for client-specific molecule development.

Basic Information

Product Name	4-Acetyl-3-Fluorobenzoic Acid Methyl Ester
CAS No.	1059549-72-2
Molecular Formula	C10H9FO3
Molecular Weight	196.18 g/mol
Synonyms	Methyl 4-Acetyl-3-fluorobenzoate; 3-Fluoro-4-acetylbenzoic Acid Methyl Ester; Benzoic acid, 4-acetyl-3-fluoro-, methyl ester; Methyl 3-fluoro-4-acetylbenzoate; 4-Acetyl-3-fluorobenzoic acid methyl ester; 1059549-72-2
EINECS	Contact for details

Quality Control

Our 4-Acetyl-3-Fluorobenzoic Acid Methyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding research and scale-up processes. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of pharmaceutical development and other high-value chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.