Description

2-Amino-3-Fluoro-6-Methylbenzoic Acid is a high-purity fluorinated benzoic acid derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of amino and fluorine substituents on the aromatic ring, which are essential for modulating the biological activity and physicochemical properties of target molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides, where the fluorine atom enhances metabolic stability and bioavailability.
• Ligand and Catalyst Development: Serves as a precursor for designing novel chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers and liquid crystals, where its structure imparts specific electronic and steric properties.
• Chemical Biology Probes: Utilized as a building block for fluorescent tags and molecular probes in diagnostic and bioimaging applications.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and production under cGMP guidelines.

Basic Information

Product Name	2-Amino-3-Fluoro-6-Methylbenzoic Acid
CAS No.	1039981-89-9
Molecular Formula	C8H8FNO2
Molecular Weight	169.15 g/mol
Synonyms	3-Fluoro-2-amino-6-methylbenzoic acid; 6-Methyl-2-amino-3-fluorobenzoic acid; 2-Amino-3-fluoro-6-methyl-benzoic acid; Benzoic acid, 2-amino-3-fluoro-6-methyl-; 3-Fluoro-6-methylanthranilic acid; 2-Amino-3-fluoro-p-toluic acid
EINECS	Contact for details

Quality Control

Our 2-Amino-3-Fluoro-6-Methylbenzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content, to ensure it meets the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.