Description

2-Amino-3-Fluoro-5-Methylbenzoic Acid is a high-purity fluorinated benzoic acid derivative serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of amino and fluorine substituents on the aromatic ring, enabling precise molecular modifications for developing novel compounds. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for creating active ingredients and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), especially in fluorinated drug candidates targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials.
• Fluorine Chemistry Studies: An important compound for academic and industrial research exploring structure-activity relationships (SAR) in fluorinated aromatic systems.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects requiring high-purity fluorinated intermediates.

Basic Information

Product Name	2-Amino-3-Fluoro-5-Methylbenzoic Acid
CAS No.	1039900-47-4
Molecular Formula	C8H8FNO2
Molecular Weight	169.15 g/mol
Synonyms	3-Fluoro-5-methylanthranilic Acid; 2-Amino-3-fluoro-5-methyl-benzoic Acid; Benzoic acid, 2-amino-3-fluoro-5-methyl-; 5-Methyl-3-fluoroanthranilic Acid; 3-Fluoro-5-methyl-2-aminobenzoic Acid; 2-Carboxy-6-fluoro-4-methylaniline
EINECS	Contact for details

Quality Control

Our 2-Amino-3-Fluoro-5-Methylbenzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and reliability for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong oxidizing agents. The container must be kept tightly closed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.