Description

n-Benzyl Tamsulosin HCl is a high-purity pharmaceutical intermediate and research chemical. This compound is critical for the development and synthesis of advanced α-1 adrenergic receptor antagonists, offering researchers and manufacturers a reliable building block for complex molecular structures. It is primarily utilized by pharmaceutical R&D laboratories, API (Active Pharmaceutical Ingredient) manufacturers, and academic institutions engaged in urological and cardiovascular research.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of Tamsulosin analogs and derivatives for research purposes.
• Active Pharmaceutical Ingredient (API) Development: Used in preclinical and process development studies for new therapeutic agents targeting α-1 adrenoceptors.
• Biochemical Research: Serves as a reference standard and ligand in receptor binding assays and pharmacological studies.
• Process Chemistry: Employed in route scouting and optimization for the scalable manufacture of related pharmaceutical compounds.
• Academic Research: Utilized in universities and research institutes for studying structure-activity relationships (SAR) of adrenergic antagonists.
• Quality Control Standard: Acts as a high-purity analytical reference material for HPLC, LC-MS, and NMR methods in quality assurance laboratories.

Basic Information

Product Name	n-Benzyl Tamsulosin HCl
CAS No.	1027854-97-2
Molecular Formula	C₂₆H₃₃ClN₂O₅S
Molecular Weight	521.07 g/mol
Synonyms	N-[(2R)-2-{[2-(2-Ethoxyphenoxy)ethyl]amino}propyl]-5-(2-benzylphenoxy)-2-methoxybenzenesulfonamide hydrochloride; Benzyl Tamsulosin Hydrochloride; Tamsulosin N-Benzyl Analog HCl; (R)-5-(2-(Benzyloxy)phenoxy)-2-methoxy-N-(2-(2-(2-ethoxyphenoxy)ethylamino)propyl)benzenesulfonamide hydrochloride
EINECS	Contact for details

Quality Control

Our n-Benzyl Tamsulosin HCl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via spectroscopic methods (NMR, IR, MS). We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing purity, impurities, and physical characteristics to ensure compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity	≥99.0% (by Chiral HPLC)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.