Description

Ethyl-3-Fluoro-4-Iodobenzoate is a high-purity, multi-functional organic building block essential for advanced chemical synthesis. This compound is valued for its unique halogenated aromatic structure, which provides versatile reactivity for constructing complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for applications such as medicinal chemistry, ligand synthesis, and the development of functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing fluorinated and iodinated aromatic systems for enhanced bioactivity and metabolic stability.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and pesticides, where the fluorine and iodine substituents can improve target binding and environmental persistence.
• Ligand and Catalyst Synthesis: Serves as a versatile scaffold for constructing specialized ligands used in transition metal catalysis and organometallic chemistry.
• Material Science: Employed in the research and development of organic electronic materials, liquid crystals, and advanced polymers.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira, Heck) due to the reactive iodine moiety.
• Fluorination Chemistry Studies: Used as a model compound in methodological development for introducing and studying fluorine atoms in organic molecules.

Basic Information

Product Name	Ethyl-3-Fluoro-4-Iodobenzoate
CAS No.	1027513-43-4
Molecular Formula	C9H8FIO2
Molecular Weight	294.06 g/mol
Synonyms	Ethyl 3-Fluoro-4-iodobenzoate; Benzoic acid, 3-fluoro-4-iodo-, ethyl ester; 4-Iodo-3-fluorobenzoic acid ethyl ester; 3-Fluoro-4-iodobenzoic Acid Ethyl Ester; Ethyl 4-Iodo-3-fluorobenzoate; Ethyl 3-Fluoro-4-iodobenzoate (CAS 1027513-43-4)
EINECS	Contact for details

Quality Control

Our Ethyl-3-Fluoro-4-Iodobenzoate is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) for every shipment. Our quality systems are designed to support cGMP and ISO standards for customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.