Description

2-Fluoro-4-Mercaptobenzoic Acid is a high-purity fluorinated benzoic acid derivative featuring a strategically positioned thiol group. This compound is valued for its dual functionality, serving as a versatile building block in advanced organic synthesis and pharmaceutical research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in molecules targeting specific enzyme inhibition or receptor modulation.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and pesticides, where the fluorine and thiol groups contribute to biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and as a building block for functionalized materials.
• Peptide Mimetics and Bioconjugation: The reactive thiol group enables site-specific conjugation and the synthesis of peptide analogs with enhanced properties.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and advanced organic frameworks.

Basic Information

Product Name	2-Fluoro-4-Mercaptobenzoic Acid
CAS No.	1026347-56-7
Molecular Formula	C7H5FO2S
Molecular Weight	172.18 g/mol
Synonyms	4-Mercapto-2-fluorobenzoic Acid; 2-Fluoro-4-sulfanylbenzoic Acid; Benzoic acid, 2-fluoro-4-mercapto-; 2-Fluoro-4-thiobenzoic Acid
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-Mercaptobenzoic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and light-sensitive nature, the container must be kept sealed under an inert atmosphere for long-term storage to prevent oxidation and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.