Description

2-Amino-3-Chloro-5-Fluorobenzoic Acid is a high-purity, multi-functional aromatic building block of significant importance in advanced organic synthesis. Its unique substitution pattern makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, leveraging the fluorine and chlorine substituents for enhanced bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials, such as semiconductors and light-emitting diodes (OLEDs).
• Fluorescent Dye and Sensor Chemistry: Acts as a core structure for synthesizing novel fluorophores and molecular probes used in bio-imaging and diagnostics.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects requiring this specific benzoic acid derivative.

Basic Information

Product Name	2-Amino-3-Chloro-5-Fluorobenzoic Acid
CAS No.	1022961-12-1
Molecular Formula	C7H5ClFNO2
Molecular Weight	189.57 g/mol
Synonyms	3-Chloro-5-fluoroanthranilic acid; Benzoic acid, 2-amino-3-chloro-5-fluoro-; 2-Amino-3-chloro-5-fluorobenzoic acid; 3-Chloro-5-fluoro-2-aminobenzoic acid; 5-Fluoro-3-chloroanthranilic acid; 2-Carboxy-6-chloro-4-fluoroaniline
EINECS	Contact for details

Quality Control

Our 2-Amino-3-Chloro-5-Fluorobenzoic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.