Description

3-Fluoro-4-Pyrrolidinobenzoic Acid is a high-purity, functionalized benzoic acid derivative featuring a fluorine atom and a pyrrolidine substituent. This compound serves as a critical pharmaceutical intermediate and advanced building block in modern organic synthesis, enabling the development of novel bioactive molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for drug discovery and process chemistry applications.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the discovery and synthesis of new herbicides, fungicides, and plant growth regulators due to its unique fluorinated aromatic structure.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Incorporated into the design of advanced polymers and organic electronic materials to modify electronic properties and solubility.
• Chemical Biology Probes: Utilized in the development of molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up campaigns.

Basic Information

Product Name	3-Fluoro-4-Pyrrolidinobenzoic Acid
CAS No.	1021243-16-2
Molecular Formula	C11H12FNO2
Molecular Weight	209.22 g/mol
Synonyms	4-(Pyrrolidin-1-yl)-3-fluorobenzoic Acid; 3-Fluoro-4-(1-pyrrolidinyl)benzoic Acid; Benzoic acid, 3-fluoro-4-(1-pyrrolidinyl)-; 3-Fluoro-4-pyrrolidin-1-ylbenzoic acid; 1021243-16-2; 3-Fluoro-4-pyrrolidinobenzoic acid
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-Pyrrolidinobenzoic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content. We provide a Certificate of Analysis (COA) with every shipment, detailing all test results against our stringent internal specifications to ensure batch-to-batch consistency and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.