Description

3-Fluoro-4-(2,2,2-trifluoroethoxy)benzoic acid is a high-value fluorinated aromatic building block of significant interest in advanced organic synthesis. Its core value proposition lies in the unique combination of a benzoic acid scaffold with fluorine and trifluoroethoxy substituents, which are critical for modulating the physicochemical and biological properties of target molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients, where its structural motifs can enhance metabolic stability, bioavailability, and binding affinity.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in oncology, CNS, and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the design and production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms contribute to improved efficacy and environmental profile.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for high-performance display technologies.
• Polymer Chemistry: Employed as a monomer or modifier to introduce fluorine-containing side chains into polymers, enhancing their chemical resistance and surface properties.
• Organic Electronic Materials: Utilized in the development of semiconductors and charge-transport materials for OLEDs and organic photovoltaics.
• Chemical Research & Development: A versatile building block for exploring structure-activity relationships (SAR) and creating novel chemical entities in academic and industrial labs.

Basic Information

Product Name	3-Fluoro-4-(2,2,2-trifluoroethoxy)benzoic Acid
CAS No.	1020998-55-3
Molecular Formula	C9H6F4O3
Molecular Weight	238.14 g/mol
Synonyms	3-Fluoro-4-(2,2,2-trifluoroethoxy)benzoic Acid; 4-(2,2,2-Trifluoroethoxy)-3-fluorobenzoic Acid; Benzoic acid, 3-fluoro-4-(2,2,2-trifluoroethoxy)-; 1020998-55-3; 3-Fluoro-4-trifluoroethoxybenzoic acid; 3-Fluoro-4-(β,β,β-trifluoroethoxy)benzoic Acid; 3-Fluoro-4-(2,2,2-trifluoroethoxy)benzoic acid (CAS 1020998-55-3)
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-(2,2,2-trifluoroethoxy)benzoic acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and process development. Certificates of Analysis (COA) detailing specific results for each batch are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.