Description

2-(Difluoromethoxy)-5-Fluorobenzoic Acid is a high-purity fluorinated benzoic acid derivative, serving as a critical building block in advanced organic synthesis. Its unique difluoromethoxy and fluoro substituents make it a valuable intermediate for creating compounds with enhanced metabolic stability and bioavailability. This product is essential for research and development teams in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially in drug discovery programs targeting metabolic and central nervous system diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, where the fluorine atoms contribute to improved efficacy and environmental profile.
• Liquid Crystal Materials: Serves as a precursor for fluorinated liquid crystal compounds used in advanced display technologies.
• Polymer Chemistry: Acts as a monomer or modifier for creating specialty polymers with specific chemical resistance and thermal properties.
• Organic Synthesis Reagent: Employed in cross-coupling reactions and as a precursor for more complex fluorinated aromatic systems in academic and industrial R&D.
• Material Science Research: Used in the development of novel organic electronic materials and coatings.

Basic Information

Product Name	2-(Difluoromethoxy)-5-Fluorobenzoic Acid
CAS No.	1017779-44-0
Molecular Formula	C8H5F3O3
Molecular Weight	206.12 g/mol
Synonyms	5-Fluoro-2-(difluoromethoxy)benzoic Acid; Benzoic acid, 5-fluoro-2-(difluoromethoxy)-; 2-(Difluoromethoxy)-5-fluorobenzoic acid; 1017779-44-0; 5-Fluoro-2-difluoromethoxybenzoic acid; DFMFBA; α,α-Difluoro-5-fluoro-o-anisic acid
EINECS	Contact for details

Quality Control

Every batch of 2-(Difluoromethoxy)-5-Fluorobenzoic Acid is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency meet the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. Due to its nature as a strong acid/organic solvent, ensure proper containment and handling procedures are followed.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.